NCPF is the only culture collection specialising in fungi (moulds and yeasts) pathogenic to humans and animals in the UK. The collection began in 1946 and was originally based in the London School of Hygiene and Tropical Medicine. The UK National Mycology Reference Laboratory (MRL) in Bristol is now the home of the collection and holds a diverse range of moulds and yeasts of clinical significance.
In total, there are over 4,000 strains from at least 100 genera. New strains are constantly added to the collection and a list of new and interesting strains will be available soon on the Culture Collections products page.
The collection encompasses dermatophytes, including many original Type strains, as well as mould isolates from sub-cutaneous and deep-seated infections, pathogenic yeast strains and strains of dimorphic fungal pathogens. A strain of recent interest is Phialemoniopsis hongkongensis HKU39 (NCPF 7868), a dematiaceous mould isolated from a forearm nodule in a compromised patient, deposited by researchers at the University of Hong Kong in 2014. This is the Type strain of a newly recognised species and it has been useful to test its susceptibility profile to further extend knowledge on the spectrum of activity of current antifungal agents.
MRL have published numerous articles using fungi from the collection; several articles have been published this year including a paper on the pathogenicity of Candida auris and other Candida species isolated in the UK. This article and others will feature in our home page feature series ‘In Research’ in coming months.
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